EASL Campus

A 54-year-old man with a BMI of 28.5 kg/m², impaired glucose tolerance, HDL Cholesterol 35 mg/dL (0.905 mmol/L) and arterial hypertension, consuming 3 beers per week, has elevated transaminases and undergoes additional exams. Abdominal ultrasound shows frank steatosis. FIB-4 is 1.85 and elastometry by VCTE reveals a liver stiffness of 8.5 kPa.

Which statement is correct?

A. The patient has MASLD but requires no further hepatological work up and can continue with his GP, with a treatment consisting of lifestyle modification

B. The patient has MASLD and requires further hepatological care. A GLP-1 is not indicated because the patient is not living with obesity and has no diabetes

C. The patient has MASH and qualifies for resmetirom once it has been approved and reimbursed

D. The patient has MASLD and requires further hepatological care. A GLP-1 can be considered

E. The patient has MetALD which requires a different approach in terms of additional assessments and pharmacological therapy

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