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Which of the following statements regarding the diagnosis of Metabolic Dysfunction-Associated Steatohepatitis is correct?

Please select the right answer:

A. Liver biopsy is required for the definite diagnosis of steatohepatitis and can help to rule out alternative causes of liver disease.

B. An increased fasting insulin (> 25 mIU/L or > 175 pmol/L) is compatible with insulin resistance, which is one of the cardiometabolic criteria that can define MASLD in the concomitant presence of documented steatosis.

C. MASLD requires the diagnosis of steatosis, which can be based on controlled attenuation parameter (CAP) with a 280 dB/m as a rule-in threshold.

D. The enhanced liver fibrosis (ELF) test is the most accurate blood-based non-invasive test for the diagnosis of advanced fibrosis.

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