A patient with Child-Turcotte-Pugh B9 cirrhosis is admitted with clinical and radiological evidence of pneumonia (community-acquired). Spontaneous bacterial peritonitis (SBP) has been ruled-out by diagnostic paracentesis. Laboratory testing reveals an increase in serum creatinine from a stable baseline of 0.9 mg/dL (79 µmol/L) to 1.3 mg/dL (114 µmol/L).